Finally having enough, Sarada stormed off. Kakashi Hatake mendapat sebelah mata sharingan dari rekannya Obito Uchiha yang dikira sudah tewas. Ia merupakan pendiri klan Uchiha dan dianggap sebagai anggota Uchiha terkuat yang pernah ada. He wraps bandages around his ankles and a blue sash around his head during this appearance. Sasuke suggests that Boruto attack Momoshiki with his Rasengan, depending on its lightning nature to catch him off guard. Having finally accepted that Itachi was a good person who was wronged by Konoha, he decides that the new mission for their team, now renamed "Taka", will be to destroy Konoha. Itachi also explained to them that, if Sasuke ever stopped by, it would be because he had died, so they share their condolences. Zetsu tells him to be patient.
Naruto disagrees, thinking he has more in common with Sasuke, but retracts and says Boruto isn't like him either. Nonetheless, he agrees to train Boruto since he already met his requirement. Sasuke is saddened by this confirmation that Itachi was a good person. Naruto and Sasuke start fighting Momoshiki with taijutsu, during the course of which Sasuke is badly burned. As B writhes in pain he nearly crushes Karin with a tentacle, prompting Sasuke to sever it to protect her. He returns Hiashi to Konoha and, while there, discovers a series of meteorites from the Moon bombarding the village.
As Momoshiki starts attacking, Naruto forms his Tailed Beast Mode around Boruto and Sarada in order to protect them; Sasuke layers his Susanoo over this to provide additional protection. Sasuke decided to do what Itachi had instructed and dedicated his life to vengeance, having no other interest than bringing about Itachi's death. By using his Rinnegan's abilities, he is ultimately able to escape. Leading up to and during his battle with Itachi, he replaces this top with a sleeveless dark grey shirt and the arm guards with bandages on his wrists. In Sage Mode, Kabuto shields his eyes so that he's immune to genjutsu. Sasuke decided to take advantage of his research being analysed to spend time a few days with his family. When they arrive, Sasuke promises retaliation against Orochimaru if he is in any way involved in the attack on his daughter or the kidnapping of his wife. Orochimaru is known to have experimented on Sasuke, enough to make him immune to poisons,  but it's not known what other modifications he may have received. Before leaving, Itachi encouraged Sasuke to hate him, to desire revenge, and to gain power from that.
After his final encounter with reincarnated Itachi, between learning of Itachi's struggles in life and knowing that Itachi made the choice willingly to become the villain for the sake of peace, Sasuke is left uncertain about what course to take. In Sage Mode, Kabuto shields his eyes so that he's immune to genjutsu. He has them perform the Tree Climbing Practice to improve their chakra control, which will help them against Zabuza.
At first, Naruto refuses because Sasuke is still in no condition to fight, but Sasuke persists and Naruto agrees. Sasuke and Suigetsu attack him with their swords, but he proves to be a better swordsman than they are and stabs Sasuke with several of his Supervibrato Lightning Release Swords. Sasuke takes the others to Sora-ku to stock up on supplies, after which he explains that their team, called Hebi , has been assembled for the sole reason of finding and killing Itachi. Sasuke reminds Naruto that only they can stop Kaguya, and therefore what happens to the others doesn't matter.
- By the time that he does, both Haku and Zabuza are dead, so their bodyguard services are no longer required.
- When they arrive, Sasuke promises retaliation against Orochimaru if he is in any way involved in the attack on his daughter or the kidnapping of his wife.
- Sasuke assists the Sixth Mizukage and Fourth Tsuchikage with restraining Kinshiki and then joins Naruto, the Fifth Kazekage , and the Fifth Raikage against Momoshiki; he warns them not to use ninjutsu since Momoshiki can absorb them.
- It isn't until Naruto brings Tsunade to Konoha that the trauma to their minds is healed.
- He rushed home to notify his family of this Uchiha Clan Massacre , only to find Itachi standing over the bodies of their parents.
- Ultimately, Sakura suggested that he should approach Sarada more like Sasuke's relationship was with his father and brother back in the day; just enjoying the time they have together and talk about their goals.
- He is also jealous of Naruto who, despite being the worst student in their Academy class, has seemingly surpassed Sasuke, evidenced by his defeat of Gaara.
Because Sasuke understands her pain and hatred, he defeats them without seriously injuring them and convinces them to accept defeat. Itachi cornered him and explained that Sasuke, as he then was, would not be worth killing. Sarada Uchiha merupakan anak dari Sasuke dan Sakura. Kakashi arrives and deflects their attacks into opposing water towers before they can clash. Although she now has access to the chakra of those trapped within the Infinite Tsukuyomi, she wants Team 7's too, specifically Naruto's and Sasuke's.
Having exhausted all of his chakra reserves and having none left to suppress Orochimaru, he emerges from Sasuke's body, attacking Itachi with his Eight Branches Technique. Sasuke and the Raikage prepare to attack each other yet again, but are stopped by Gaara , now the Kazekage. He ignores her questions and says his actions have nothing to do with her, causing her to storm out, crying. Sasuke tries to get up, determined to not let Madara win and, in turn, let Itachi's memory be sullied, but he passes out as the life fades from him.